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Objectives: The aim of this study was to investigate the association between self-esteem and temporomandibular disorder among high school students. Methods: A self-reported questionnaire was completed by 584 high school students in Gyeongnam. The questionnaire consisted of socio-demographic profile, anxiety, self-esteem, oral parafunctional habits, and temporomanibular disorder. Data were analyzed using SPSS 19.0 program. Results: In univariate analysis, there were significant differences between self-esteem and temporomandibular disorder(p<0.05). The self-esteem was negatively correlated with parafunctional habits(r=-0.253, p<0.001) and temporomandibular disorder(r=-0.221, p<0.001). In multivariate analysis, self-esteem was significantly associated with temporomandibular disorder(β= -0.119, p=0.025) after adjusting for socio-demographic characteristics and anxiety. Conclusions: The self-esteem negatively influenced on temporomandibular disorder in the high school students.