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This study was undertaken to investigate the influence of multi-probiotics, fermented ginseng byproducts and fermented sulfone as an alternative to probiotics on performance, intestinal microflora and immunity of broiler. A five weeks trial was conducted with one day old Ross×Ross broilers (n=340), divided into five groups which further divided into 4 replicates with 17 birds in each replicate. Birds were assigned to 5 dietary treatments as control, antibiotic avilamycin (AB), multi-probiotics (MP), fermented sulfone (FS) and fermented ginseng byproducts (FGB). Growth parameters were recorded on weekly basis while rest of the parameters viz. blood and faeces were collected at the end of the experiment. Growth parameters were not affected statistically by dietary treatments. However, numerically, higher body weight, splenocytes proliferation and lower total cholesterol and LDL values were found in MP treatment (P>0.05). Salmonella spp. count (P≤0.001) and E. coli (P<0.001) concentrations in the ileum were found lowest in AB treatment while FS group showed lowest level of yeast (P<0.10) and Lactobacillus spp. (P≤0.001). Fecal ammonia and CO2 emission was significantly decreased in FGB than other dietary treatments (P<0.05). It was concluded that multi-probiotics would be valuable feed additives to improve the growth performance, Lactobacillus proliferation and immunity of broiler chicks.