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The cavity liners and bases were used to provide a barrier or protective layer between the exposed dentin and final restoration. This buffer layers might act to reduce or even eliminate postoperative sensitivity. Recently, their light-activated derivatives were introduced as new products. Since many of the new products introduced as a cavity liner or a cavity base, the core properties (such as solubility, acid erosion, ion release, strength, radiopacity and biocompatibilities) of those products should be evaluated based on the proper International Standards and Specifications. For preclinical test, several core properties of eleven commercial products (calcium hydroxide, zinc oxide phosphate, zinc oxide eugenol, glass ionomer, and hydroxyapatite) were tested. Solubility, acid erosion, compressive strength and flexural strength,radiopacity, and cytotoxicity were evaluated according to the International Standards (ISO 3107, 4049,9917-1, and 9917-2). Almost all experimental groups (zinc oxide eugenol, zinc phosphate, and glass ionomer cements) except for calcium hydroxide groups were met the requirements of ISO specifications. As there were no ISO specifications for the dental calcium hydroxide, it was necessary for suggestion for the guideline of calcium hydroxide products to evaluate those products properly. Commercially available products tested in this study showed proper physical and biological properties for clinical applications.