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The purpose of this study is to investigate effects of 12 weeks of combined exercise program on basic physical strength and health-related parameters in industrial sector workers. Fifty untrained volunteers were divided to low frequency group (2 times or less/week; 2-LG, n=20) and high frequency group (3times or more/week; 3-HG, n=30). All subjects participated to combined exercise program (resistance exercise: 1RM-60-70%, 8-12 repetitions, 2 sets, 1 min rest between each set, endurance exercise: RPE 15±2, 20 min, and exercise ball: 10 min). Basic physical strength (squeeze, sit and reach, sit-up, 1000m) and health-related parameters (weight, blood pressure, blood glucose, total cholesterol, triglyceride, WHR, body fat, muscle mass) were measured before and after of the combined exercise program. Squeeze, sit and reach, 1000m, WHR, body fat, and muscle mass improved significantly in 3-HG (p<.05). Sit-up and weight also improved significantly in both group (p<.05). These data indicated that the combined exercise program of 12 weeks mediate positive effects on basic physical strength and health-related parameters, and participation of the exercise three times or more a week might be needed to benefit of exercise application and health care.