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BThere are many materials which can make beautiful, clear eyelid crease with temporary effect. Double fold tape and glue are the most popular materials to make artificial double eye lids. However, the long-term use of these materials seems to make cause many local problems. This study was conducted to identify the long-term side effects of double-fold tape and glue. A total of 191 patients who have experienced double fold tape or glue were enrolled. The information of age, double-fold making product, and side effects were collected, based on medical records and, Patient & Observer scale(1: 'Normal', 5: 'Abnormal/Severe). The mean period of use was 23.7 months. The time required to make double-fold was 5~30 minutes. The most common symptom was itching sense, followed by decrease skin elasticity, skin dryness, and change of skin color. The most common signs was skin laxity, followed by eruption, keratinization, pigmentation, and local inflammation. One patient underwent medical treatment for conjunctivitis after double-fold glue usage. Double fold tape or glue can lead a problem with skin due to lack of oxygen exposure and rubbing eye lids with a stick. Appropriate use of double-fold products and careful monitoring of side effects are needed. (Archives of Aesthetic Plastic Surgery 17: 123, 2011)