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This paper treats with transitional development of medico-hygienical situation in district Yanbian along with the evolution in specific field of medicine. This work is particularly important in shaping TKM identity as TCM embraces Chao medicine asserting it as one included in TCM. This research deals with themes of migration of Chao minorities to this territory and their medico-hygienical situation. Lifted bans on immigration in late Qing dynasty with uncertainty of Korea(Chosun) triggered the immigration to this district. The flow was heavily strengthened under the influence of Westerners and Japanese imperialism into china which consequently provoked the ruin of Qing dynasty, the civil war between republicans and communist and the socio-political changes in Korea. As population growths, the establishment of hospitals and immigration of healthcare professionals were also increased. Though this district is located in Chinese mainland the influence of Japanese was also relevant which lead to medical practice reflecting both sides. Mutual combination and influence of western(contemporary) medicine, TCM and TKM practices made the particularity of Chao medicine.