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The aim of this review is to understand the complex clinical features and courses of bipolar II disorder. This article is based on the review of articles related to the clinical features and courses of bipolar II disorder. The papers included in this review were selected on the basis of the quality of findings related to the review topic. Bipolar II disorder is not a less severe variant of bipolar I disorder. Bipolar II disorder, compared with bipolar I disorder, has a substantially mo- re chronic course, significantly more suicidal risks, more comorbidities, and shorter inter-episode well-functioning pe- riods. Understanding of comorbidities and mixed depression, more common in bipolar II disorder compared with other mood disorders, is essential to identify complex clinical feature and course of Bipolar II disorder.