초록 close

마취가스로 사용되는 아산화질소(N2O)는 만성건강 잠재위험을 일으킬 수 있기 때문에 근무자를 보호 하기 위해 아산화질소 노출을 감시하고 제어하는 것이 필요하다. 이 연구에서는 아산화질소 노출평가를 위해서 흡착제로는 molecular sieve 5A를 사용하였고 7㎖ vial에 보관한 후 heating block에서 100℃로 12시 간 이상 가열하여 GC-ECD를 이용하여 분석, 평가하였다. GC-ECD에 의한 검량선 설명력계수(R2)는 0.9992이며 검출한계는 0.96㎍/injection, 정량한계는 3.21㎍/injection, 탈착효율은 평균 94.78 ± 4.50%이 다. 파과는 각 농도대비 10% 범주 내에 있었다. GC-ECD에 의한 N2O의 수술 전과 수술 중의 노출평가에서 는 수술 전의 평균농도는 5.12ppm이고 수술 중의 평균 농도는 42.33ppm으로 수술 중의 아산화질소의 농 도가 높게 나타났고 중대한 차이가 있다(P<0.05). GC-ECD에 의한 N2O의 근무자의 근무위치에 따른 노출 평가에서는 중대한 차이가 없고(P>0.005), 시료채취 법에서는 능동식 시료채취 법에서의 N2O 농도가 높 게 나타났다(P<0.05).


Nitrous oxide, which is used as an anesthetic gas, has been shown to be a chronic health hazard. It is necessary to monitor and control the nitrous oxide exposure of the operating theaters staff. In this study, N2O exposure level of the operating nurses is assessed with a GC-ECD. The nitrous oxide gas is collected on a molecular sieve 5A contained in a glass tube and desorbed for 12 hours at 100℃ in heating block. As a result of the test using GC-ECD, calibration curve's R2 of N2O is 0.9992, LOD is 0.96㎍/injection, LOQ is 3.21㎍/injection, desorption efficiency is 94.78 4.50% in average and break through is within 10% compared with the concentration. The average concentration before operation is 5.12ppm and it is 42.3ppm during operation. There are a significant difference showing that the P value is lower than 0.05. Assessing exposure level to nitrous oxide based on nurses' working positions, the exposure levels do not show significant difference( P>0.005). And N2O in active sampling method is higher than passive sampling method(P<0.05).


Nitrous oxide, which is used as an anesthetic gas, has been shown to be a chronic health hazard. It is necessary to monitor and control the nitrous oxide exposure of the operating theaters staff. In this study, N2O exposure level of the operating nurses is assessed with a GC-ECD. The nitrous oxide gas is collected on a molecular sieve 5A contained in a glass tube and desorbed for 12 hours at 100℃ in heating block. As a result of the test using GC-ECD, calibration curve's R2 of N2O is 0.9992, LOD is 0.96㎍/injection, LOQ is 3.21㎍/injection, desorption efficiency is 94.78 4.50% in average and break through is within 10% compared with the concentration. The average concentration before operation is 5.12ppm and it is 42.3ppm during operation. There are a significant difference showing that the P value is lower than 0.05. Assessing exposure level to nitrous oxide based on nurses' working positions, the exposure levels do not show significant difference( P>0.005). And N2O in active sampling method is higher than passive sampling method(P<0.05).