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Objectives : The aim of this study was to assess the relationship between risk factors, warning signs, tongue diagnosis, pulse pattern, pattern identification and National Institute of Health Stroke Scale in acute stroke patients. Methods : We studied hospitalized patients within 4 wks after their ictus who were admitted at the Internal Medical Department at Kyunghee oriental medical center, Kyunghee university East-West Neo medical center, Kyungwon university Songpa oriental medical center, Kyungwon university Incheon oriental medical center, Dongguk university Ilsan oriental medical center from April 2007 to August 2009. We analyzed the relationship between risk factors, warning signs, tongue diagnosis, pulse pattern, pattern identification and National Institute of Health Stroke Scale in acute stroke patients. Results : 1506 subjects were included into the final analysis. 1. In the risk factors, the NIHSS mean score of Atrial fibrillation is significantly higher than Non-Atrial fibrillation. 2. In the warning signs, the NIHSS mean score of Weakness, Loss of eyesight, Dysarthria, Sensory loss are significantly higher than Non-warning signs. 3. There was no significant difference of Lifestyle, Tongue fur color, Pattern identification between groups. 4. In the Tongue color, the NIHSS mean score of red is significantly higher than pale and pale red. 5. There were significant results statistically between forceful/weak, fine/not fine, slippery/not slippery pulse and NIHSS score. Conclusion : The above results showed that the relationship between risk factors, warning signs, tongue diagnosis, pulse pattern, pattern identification and National Institute of Health Stroke Scale in acute stroke patients. These results can be utilized in the future as a basis material.