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Purpose: The purpose of this study was to find out the research trend and analyze the evidence of research on massage interventions for patients in Korea. Methods: Literature database search from 2003 to 2008 was carried out including KSTUDY, RICHIS, RISS4U, and NANET using the following MeSH terms: massage and patients. Results: A total of 51 articles registered in Korea Research Foundation were reviewed for analysis. Major participants of the studies were patients with cancer, surgery patients, stroke patients, and preterm babies. The outcome variables most commonly measured were blood pressure, state anxiety, and pain. While massage intervention was reported having a significant effect on lowering anxiety and pain, the other effects of massage in patients were inconsistent. Conclusion: Massage intervention has evidence-based effects on reducing anxiety and pain in patients. A larger body of methodologically sound research is needed to verify the multidimensional effects of massage.