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목적: 빛간섭단층촬영으로 측정한 망막신경섬유두께와 중심각막두께의 관련성을 고찰하고자 하였다. 대상과 방법: 녹내장 100안, 녹내장의증 99안에서 시야 검사, 빛간섭단층촬영, 중심각막두께를 측정하고 지표들의 관련성을 Pearson correlation 분석을 통해 알아보았다. 중심각막두께와 망막신경섬유두께의 상관관계를 mixed effect model을 통해 분석하였고 얇은 각막군(553.6 µm >)과 두꺼운 군으로(553.6 µm ≤) 나누어 양 군 간에 세 지표, 시야검사 mean deviation (MD), pattern standard deviation (PSD), 망막신경섬유두께의 차이를 비교하였다. 결과: 전체 대상안에서 중심각막두께와 망막신경섬유두께의 관련성은 관찰되지 않았다(R²=0.00, p=0.88). 녹내장군과 녹내장의증군에서 중심각막두께와 망막신경섬유두께는 각각 유의한 상관관계를 보이지 않았다(p=0.11, p=0.46). 얇은 각막군과 두꺼운 각막군 간에 세 지표는 유의한 차이를 보이지 않았다(p=0.38, 0.32, 0.44). 결론: 녹내장과 녹내장의증군에서 중심각막두께는 망막신경섬유두께와 유의한 관련성을 보이지 않았다.


Purpose: To evaluate the correlation between central corneal thickness (CCT) and retinal nerve fiber layer thickness (RNFLT) as determined by optical coherence tomography (OCT) in glaucomatous subjects. Methods: One hundred eyes diagnosed with glaucoma and 99 glaucoma suspect (GS) eyes were tested by visual field (VF), OCT, and ultrasonic pachymetry. The relationship between CCT and RNFLT measurements was assessed by Pearson correlation analysis. A mixed effect model was employed to determine the relationship between CCT and RNFLT in glaucoma and GS groups. We divided the patients into two groups depending on the thickness of their corneas: Thin (< 553.6 µm) and thick (≥ 553.6 µm), and compared three parameters: VF mean deviation (MD), pattern standard deviation (PSD), and RNFLT between the two groups. Results: There were no significant correlations between CCT and RNFLT in any participant (R²=0.00, p=0.88). There was no significant relationship between CCT and RNFLT in glaucoma and GS groups (p=0.11, p=0.46). There were no statistically significant differences in MD, PSD, or RNFLT between the thin and thick cornea groups (p=0.38, 0.32, 0.44). Conclusions: CCT is not significantly associated with RNFLT in glaucoma and GS subjects.