초록 close

사람면역결핍바이러스 감염 환자는 여러 이유로 혈전증이 발생하기 쉽다. 저자들은 단백질 S 결핍과 항카디오리핀 IgG 증가와 연관하여 신정맥혈전증이 발생한 1예와 수척증후군으로 megestrol acetate 사용 중에 하지의 심부정맥혈전증과 폐동맥혈전증이 발생한 2례를 경험하였다. 본 증례들은 사람면역결핍바이러스 감염 환자에서 심부정맥혈전증에 대한 주의가 필요함을 시사한다.


Patients with HIV infection may be at increased risk of thrombosis. A variety of mechanism have been proposed to account for hypercoagulability in HIV-infected patients. These include decreased plasma concentrations of protein S, opportunistic infection, tumor such as Kaposi's sarcoma, drugs such as megestrol acetate, protease inhibitor, and presence of anticardiolipin antibody. The authors report three cases of thrombosis in AIDS patients. One case was renal vein thrombosis associated with abnormalities of protein S and anticardiolipin IgG. Two cases were pulmonary embolism associated with megestrol acetate.