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구강 종양은 대부분 원발성으로 발생하며, 구강 종양의 1∼4%만이 전이성 암이다. 폐암의 치은으로의 전이는 뒤늦게 발생하며, 매우 드물게 보고되고 있다. 저자들은 56세 남자 환자가 비소세포폐암을 진단받은 후 1차와 2차 항암화학요법을 시행 받았으나, 원발암이 진행으로 다발성 전이와 함께 우연히 상악 치은에서 종양이 발견되어 절개 조직검사 시행 후 전이성 폐암이 진단된 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.


About 5% of all malignancies involve the oral cavity. Metastatic cancers to the oral cavity from distant sites are very rare, and only a few cases have been reported in the clinical literature. The most common tumors that metastasize to the oral cavity originate in the breast, lung, and kidney. We recently experienced a patient who had a non-small cell lung cancer that metastasized to the gingiva. The patient was 56-year-old man. The disease status was a progressive condition, although the patient had received third-line chemotherapy. The patient had multiple bony metastases including vertebral bodies, femurs, and clivus as well as the gingival metastasis. The gingival tumor was histopathologically diagnosed as a poorly differentiated adenocarcinoma. The metastatic gingival tumor had the same pathology as the primary lung cancer. (Korean J Med 73:661-665, 2007)