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Osteomyelitis of the maxilla is a relatively rare disease. Although the advent of antibiotics has decreased its incidence and morbidity significantly, osteomyelitis still remains a potentially dangerous condition because of the possible risk of intrace-rebral complications. Clinically, patients present facial swelling, localized pain and tenderness, low-grade fever, draining sinus tracts, suppuration, dental loss, and sequestrum formation. We experienced a case of osteomyelitis of the maxilla with associated aspergillosis. In this paper, we report this case with a review of literature. (Korean J Otolaryngol 2002;45:511-4)