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Epidural cysts, either synovial or ganglion, are an unusual cause of spinal epidural compressive syndromes. Ganglion cysts are a rare cause of lumbosacral radicular compression, especially in young people. The authors report two ganglion cysts located in the spinal canal of two patients. The lesions were demonstrated by a magnetic resonance imaging, and relief of symptoms was achieved with laminectomy and total removal of the mass. The clinical and radiological evaluation and treatment of these lesions are discussed.