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The purpose of this study was to determine the effects of training patterns on serum leptin, insulin and plasma free fatty acids(FFA) as well as swim performance in highly competitive swimmers. Foruteen highly trained collegiate male swimmers were recruited and divided into two groups: either taper group (EXT: 19.86±1.57yrs; 175.86±4.10cm) or non-taper group (CON: 19.86±1.35yrs; 179.43±6.16cm). Subjects in EXT performed three training protocols which was 2 weeks de-training period, 8 weeks normal training period and 2 weeks taper period, while subjects in CON performed only two training protocols that consisted of 2 weeks de-training period and 10 weeks normal training period. Each training sessions were completed, all subjects undertook 100m sprint swimming and blood samples were taken for leptin, insulin and FFA concentration measurement. Following taper period, there was a not significantly faster 100m sprint swimming performance in EXT compared to CON. Sprint swimming record was also not significantly improved following taper period compared to normal exercise training period in EXT (56“70±2.03 second for normal training period vs. 55”99±2.11 second for taper period).The concentration of resting leptin, insulin and FFA from EXT was not significantly changed but FFA concentration was significantly altered in CON which did not have taper period. In conclusion, serum leptin and insulin concentration were not sensitive to prolonged intensity training and FFA was changed that training volume and duration. these data suggest that leptin may not be useful in monitoring relative swim training stress in highly competitive swimmers.