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The purpose of this study was to investigate the effects of the resistance exercise with aerobic exercise program on body composition and ECG response in the severe obesity women. The subjects consisted 12 severe obesity women, who was aged 20~30years were checked by a body composition and exercise stress testing. In measurement index, body composition analysis were measured of percent body fat, body fluid, BMI and WHR. And exercise stress testing were measured ST segment, ST/HR slope, ECG interval, and QRS vector. We enrolled 12 severe obesity women into the participated 12 week exercise training program. Statistical analysis was performed using analysis of paired t-test. Results of this study were as follows; In the body composition, weight, percent body fat, body fluid, BMI, and WHR were showed significantly effects of exercise program participation in the all index. In the ST segment, ST level were increased at peak exercise in read V2 and V5, and ST slope were decreased at peak exercise in the read V2 and V5. ST/HR slope of read V2 and V5 were increased significantly exercise program participation after than before in exercise peak, recovery three min. In the ECG interval, P-R and QRS interval were showed no significant, but ST, QT, and QTc interval were prolonged significantly exercise program participation after than before. In the QRS vector, frontal axis of resting and recovery was tend to right axis deviation significantly exercise program participation after than before. And, in the amplitude of QRS vector, resting and recovery was tend to longer significantly exercise program participation after than before. These data suggest that 12 week exercise training program in severe obesity women is an effective to improve body composition and cardiac function. Conclusionally, severe obesity women will no longer be a rare event, and providers have to prepare to treat such patients on a regular basis.