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Purpose. This correlation study was undertaken to examine the relationships between daily life stress, self-efficacy and university student life adjustment and to analyze the self-efficacy affecting that university student life adjustment. Methods. 265 university students were recruited from several participating required undergraduate classes. They were surveyed as the subject of this study. Data collection was conducted through the use of questionnaires. Results. The university life adjustment level showed a maximum score of 9 with the mean score 5.22. A negative correlation was found between daily life stress and university life adjustment. Also, there was positively correlation between self-efficacy and university life adjustment. Self-efficacy and daily life stress accounted for 23% of the variance in university student life adjustment. Conclusion. According to the results, self-efficacy is a useful concept in helping overall university life adjustment. Therefore, university student consultation office or nurse should consider the program based on selfefficacy in order to help university students to better adapt to university life.