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Purpose:The purpose of this study was to explore the psychosocial adjustment process in adolescents with epilepsy in the context of Korean society and culture. Method: A grounded theory method was used for data collection and analysis. Participants for this study were 9 adolescents who regularly visited an epilepsy clinic in a university hospital. The data was collected through in-depth interviews during the period from November, 2002 to June, 2003. Data collection and analysis were performed simultaneously. Result: Twenty-three categories emerged including 'suffering', 'psychological stigma', and 'social isolation from one's peers'. Categories were divided into paradigms which consisted of conditions, actions/ interactions, and consequences. 'Reconstructing life' was the core category in this study. The theoretical scheme was described by organizing categories around the core category. Conclusion: This study provides a framework for the development of individualized nursing interventions to care for adolescents with epilepsy.