초록 close

라트케열 낭은 일반적으로 증상이 없어 부검상 우연히 발견되는 터키안 혹은 터키안주위에 위치하는 비신생물의 상피성 병변이다. 저자들은 두통, 뇌하수체 기능저하증 등의 증상을 동반하여 낭종 부분절제술을 시행한 라트케열 낭 환자 7예를 병리학적으로 확진하여 내분비학적 특징을 분석하여 보고하는 바이다.


Rathke's cleft cyst is a cystic sellar or suprasellar lesion thought to originate from the remnants of Rathke's pouch. It is characteristically lined by a single layer of ciliated cuboidal or columnar epithelium. Although small asymptomatic Rathke's cleft cysts have been reported at autopsy in 2~26% of normal pituitary glands, symptomatic cysts are rare. For patients with symptomatic Rathke's cleft cysts presentation with headache, pituitary dysfunction, and visual loss caused by compression of the optic chiasm in the event of suprasellar extension, is common. We report the endocrine characteristics of seven cases of patients with symptomatic Rathke's cleft cyst diagnosed with pathologic confirmation. (J Kor Endocrinol Soc 22:74~79, 2007)