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In molecular imaging studies via magnetic resonance imaging, in vivo cell tracking is an important issue for the observation of cell therapy or disease behavior. High resolution imaging and longitudinal study are necessary to track the cell movement. Since the field inhomogeneity extends over several voxels, we have performed the numerical analysis using the sub-voxel method dividing a voxel of MR image into several elements and the information about the field inhomogeneity distribution around the micro-beads. We imbedded ferrite-composite micro-beads with the size of 20-150 μm in the subject substituted for cells to induce local field distortion. In the phantom imaging with the isotropic voxel size of 200 μm3, we could confirm the feasibility of sub-voxel tracking in a 3.0 T MRI.