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Once assessment of material failure characteristics is captured precisely in a unified way, it can be directly incorporated into the structural failure assessment under various loading environments, based on the theoretical backgrounds so called Local Approach to Fracture. The aim of this study is to develop a numerical fatigue test method by continuum damage mechanics applicable for the assessment of structural integrity throughout crack initiation and structural failure based on the Local Approach to Fracture. The generalized elasto-visco-plastic constitutive equation, which can consider the internal damage evolution behavior, is developed and employed in the 3-D FEA code in order to numerically evaluate the material and/or structural responses. Explicit information of the relationships between the mechanical properties and material constants, which are required for the mechanical constitutive and damage evolution equations for each material, are implemented in numerical fatigue test method. The material constants selected from constitutive equations are used directly in the failure assessment of material and/or structures. The performance of the developed system has been evaluated with assessing the S-N diagram of stainless steel materials.