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In order to utilize different nitrogen sources and tosurvive in a situation of nitrogen limitation, microorganisms haveto a changing nitrogen supply. In this comunication, therecent knowledge of nitrogen regulation in the amino acidproducer Corynebacterium glutamicum is sumarized. Thecore adaptations of C. glutamicum to nitrogen limitation onthe level of transcription are controlled by the global regulatorAmtR. Further components of the signal pathway are GlnK, aP