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Purpose: The purpose of this study was to verify the effect of aromatherapy hand massage on the anxiety of gastroscopy clients. Method: The data were collected during the period from March 10 to May 20, 2004 at S-Hospital in Kyungi-Do. There were sixty subjects, 30 for the experimental and 30 for the control group. The data were analyzed by descriptive statistics, t-test, χ²-test and paired t-test with SPSS program. Result: The pulse rate was reduced significantly, but there were no significant differences in the systolic and diastolic blood pressure between two groups. The status anxiety of experimental group was lower than the control group, but there was no significant difference statistically. Conclusion: Aromatherapy could be useful in the nursing practice, and be utilized as a way of nursing intervention to reduce anxiety of the client in specific clinical situations.