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helps to search for the set of genes associated with a specific disease or the set of diseases associated with a specific gene. Despite recent improvement of natural language processing (NLP) and other text mining approaches to search for disease associated genes, many false positive results come out due to diversity of exceptional cases as wel as ambiguities in gene names. In order to overcome the weak points of current text mining approaches, MediScore introduces statistical normalization based on binomial to normal distribution approximation which corects inaccurate scores caused by comon words not representing genes and positive results. Interactive rescoring includes individual alias scoring for each gene to remove false gene synonyms, refering MEDLINE abstracts, and cross referencing between OMIM and other related information.Availability : Mediscore is frely available from htp:/www. ngri.re.kr/mediscore.Suplementary Information : http://w.ngri.re.kr/mediscore/ manual