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analgesic and the antipyretic activity of the methanol, chloroform, hexane and acetonitrile extractsof the aerial parts of Stachys schimperi Vatke were investigated in mice. The nociceptive response was testedinduced fever test. The chloroform extract at 50 mg and hexane and acetonitrile extracts at 250 mg producedsignificant analgesic and antipyretic activity. KeywordsStachys schimperi, analgesia, hypothermia