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study investigates the chemical components and biological activities in Picrasma quassioides (D. Don) Benn.extracts for the purpose of developing natural pharmaceutical products. The proximate components in Picrasma quassioides(D. Don) Benn. extracts were 81.56% of carbohydrate, 5.80% of crude fat, 7.75% of crude protein, and 2.07% of crude ash.Calcium was the most predominant mineral and folowed phosphorus, potassium, sodium, and magnesium, in a decreasingorder. The content of the unsaturated faty acids, such as oleic acid, linoleic acid, and linolenic acid, was find to be higher thanthose of saturated fatty acids. Water and methanol extract exhibited antioxidative activity with IC50 of 128g/ml and 144g/Picrasma quassioides (D. Don) Benn.extracts. The α-glucosidase inhibitory activity showed that methanol and water extract were the high inhibitory activity. Con-sidering these results, water extracts of Picrasma quassioides (D. Don) Benn. showed the possibility that they can be used asa new material for natural pharmaceutical products.Key wordsantioxidative activity, chemical components, Picrasma quassioides (D. Don) Benn., biological activities, waterextracts .... (Picrasma quassioides (D. Don) Ben.). ..... ..... , ..... (Simaroubaceae). ... .. ...... .. ... .... . .. . 10 m .... , .. .... .. 9~15.. .. ... .... ... . ... ...10 cm .... ... ... .. , ... . (. ) ...