초록 close

저자들은 위 내시경 및 내시경 초음파에서 2.5×2.0 cm의 점막하 종양을 수술로 치료하였다. 수술 후 조직검사 결과 광학 현미경 검사에서 종양은 방추형세포로 구성되어 있었고 가장자리에 두꺼운 림프구층으로 구성되어 있으며, 면역조직화학적 검사에서 S-100 단백에 미만성 강양성을 보이고 CD34, smooth muscle actin, desmin에 음성인 위 신경초종 1예를 경험하였기에 보고하는 바이다.


Most submucosal tumors of the stomach are of mesenchymal origin. Gastric schwannoma, which is a subset of mesenchymal tumors, is a rare tumor taking origin from Schwann's cells.A 61-year-old woman whose endoscopy showed a well circumscribed submucosal mass measuring 2.5 cm on the midbody of the stomach. Endosonographically, the tumor was well circumscribed, low echoic submucosal mass with cystic lesion in the 4th layer of the gastric wall. The patient underwent wedge resection. Microscopically, the cells were made up of irregular fasciculating bundles of spindle cells featured with benign nuclear atypia and peripheral lymphoid cell cuffing, involving muscularis propria. Immunohistochemical staining showed positivity for S-100 protein and the neuron-specific enolase, but were negative to CD 34, desmin and smooth muscle actin. From these findings, this tumor was diagnosed as a schwannoma. (Korean J Gastrointest Endosc 2002;24:156 160)