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The purpose of this study was to suggest the feature, problem, and solution of interior design of middle- and large-scale dental clinics newly opened recently in Korea to propose the direction of planning the middle- and large-scale dental clinics had to adopt in its interior design in the future. Study samples were selected from actual examples of newly opened middle- and large-scale dental clinics planned and designed by specialized interior architects, and then they were analyzed by the factors of interior design. Study findings revealed that the direction of planning according to the feature, problem, and solution of the interior design of middle- and large-scale dental clinics could be proposed as follows:The case study of middle- and large-scale dental clinics could be summarized for the primary factors such as the composition and formation of space, the feature of the moving line of space, the problems and solutions of such spaces are analyzed.