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The purpose of this study was to analyze the effect of resistance exercise prescription on body composition, abdominal fat and coronary risk factors in the severe obesity middle- aged women. Eight severe obesity middle-aged women were selected to perform the resistance exercise prescription with in 55∼70% RM, for 60min/day, 3∼4 times/week during 12 weeks. The statistical techniques utilized in the study were paired t test analysis. The .05 level was initially established in significance. The conclusions of the study were as follows; In the body composition, abdominal fat function there were significant difference on the body weight, total body fat, percentage of fat, body mass index, total abdominal fat, visceral fat volume, subcutaneous fat volume, and visceral-to-subcutaneous fat volume ratio were significantly decreased. In the coronary risk factors function there were significant difference on the TC, TG, LDL-C and AI were significantly decreased, HDL-C was significantly increased.