초록 close

The cytotoxic activity of 13(E)-labd-13-ene-8α,15-diol (1) was evaluated against tumor cell lines. A comparison of IC50 values of this compound in cancer cell lines showed that their susceptibility to this compound decreased in the following order: P388 > B16/F10 > MDA-MB-231> A549 > KB > SNU-C4 by the MTT method. 13(E)-Labd-13-ene-8α,15-diol (1) was the most effective growth inhibitor of P388 murine leukaemia cell lines, producing approximately 8.3 μg/mL of IC50 in the MTT method.