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The immune activities of Ganoderma lucidum Mycelium added garlic extracts (GAM), Ganoderma lucidum Mycelium (GM), garlic extracts (GS) and standard (β-glucan) were compared. GAM enhanced the growth of human immune T cell up to 1.25~1.46 times, compared to control group. GAM showed relatively lower cytotoxicity in using normal human lung cell, while GAM showed the most potent inhibitory effect on the human lung carcinoma, compared to GM and GS. The selectivity of GAM was also as well as the growth of human immune cells. It can imply that GAM has higher immune activity than GM or GS.