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Peripheral neuropathies occur in lymphoma patients. Causes of neuropathy include chemotherapy, opportunistic infections, and the lymphoma itself. We report a patient with lymphoma whose chief complaint was a sensory loss in the hands and feet. Electrophysiologic studies and sural nerve biopsy showed sensory polyneuropathies. We hypothesize that this neuropathy is associated with lymphoma-related ganglio-nopathy, and among the possible causes, we suspect that a systemic cause such as a paraneoplastic syndrome is the most likely pathogenic etiology. However, further follow-up will be necessary to see whether sensory symptoms change with lymphoma treatment.


Peripheral neuropathies occur in lymphoma patients. Causes of neuropathy includechemotherapy, opportunistic infections, and the lymphoma itself. We report a patientwith lymphoma whose chief complaint was a sensory loss in the hands and feet. Electrophysiologic studies and sural nerve biopsy showed sensory polyneuropathies. We hypothesize that this neuropathy is associated with lymphoma-related ganglio-nopathy,and among the possible causes, we suspect that a systemic cause such asa paraneoplastic syndrome is the most likely pathogenic etiology. However, furtherfollow-up will be necessary to see whether sensory symptoms change with lymphomatreatment.