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Mesenteric vein thrombosis is an uncommon but important clinical entity and can cause ischemia or infarction of the small intestine. It is usually caused by various conditions such as hypercoagulable states, portal hypertention, trauma, pancreatitis, peritonitis, inflammatory bowel disease, and intraabdominal abscess. Both acute and chronic pancreatitis induces various vascular complications, and major part of venous complications are thrombosis of the splenic or portal veins. Thrombosis of the superior mesenteric vein without simultaneous thrombosis of the splenic or portal vein may occur in cases of pancreatic neoplasm or intraabdominal sepsis, but it is very rare. We report a case of superior mesenteric vein thrombosis in acute pancreatitis which was cured without anticoagulation therapy.