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The brain functions were investigated by analyzing the power of alpha frequency band in three phases of science problem solving. The three phases are during the pre-reading rest stage, during the process of reading the science problem, and while thinking of a solution to the science problem. The subjects were, 27 in number, all 2nd year middle school students. Electroencephalographic (EEG) activity was monitored over 8 scalp locations representing the frontal (F3, F4), the temporal (T3, T4), the parietal (P3, P4), and the occipital (O1, O2) lobes. A fast Fourier transform (FFT) was performed to derive a spectral power average in the alpha band (9∼11Hz), and EEG topography of the relative alpha activity was made in each phase of problem solving.In each phase of science problem solving, the alpha activity was the highest value in the parietal lobe and the lowest value in the frontal lobe. The alpha activity decreased significantly in the left and right frontal lobes during the reading and problem solving phases compared to the pre-reading rest phase. And there was no significant difference in alpha activity between the left and right brain hemispheres in each phase of science problem solving.The results suggest the functions of frontal lobe are activated to solve the science problems and a brain hemispheric dominance during science problem solving don't appear in middle school students.