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Neurilemomas are tumors arising from the myelin-producing Schwann cells of the peripheral nervous system. Neurilemmomas of the 12th cranial nerve are rare, with most originating intracranially. The rarity of such pathology in the submandibular space salivary gland tumor. The preoperative diagnosis of hypoglossal nerve neurilemmoma in this region is very important in that the patient must be warned of the morbidity of sacrificing the nerve during surgical excision and that the surgeon might be prepared for nerve graft. Therefore, we report recent experience of 2 cases of hypoglossal nerve neurilemmomas occuring in the subman-dibular area with a review of literature focusing on radiological findings and preoperative differential diagnosis. (Korean J Otolaryngol 2003 ;46 :1088-91)