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Background and Objectives:Laser-asisted uvulopalatoplasty (LAUP) is well established in the treatment of snoring and obstructive slep apnea syndrome (OSAS), although most reports are based on short-term follow-up results. This study was performed to determine the long-term effects on symptoms and polysomnographic measures in patients with OSAS after 5yrs of LAUP. :Fifty patients with OSAS underwent LAUP, and of these patients, 20 have completed post-operative polysomnographic studies. Questionnaires ranking snoring and apneic symptoms were completed by the patient and bed partner before LAUP. The parameters of measurement were apnea index (AI), respiratory disturbance index (RDI), SaO2, and sleep stages. The statistical analysis was performed using Wilcoxon signed rank test. Results:Subjective ques-The symptomatic improvement persisted long time. The AI decreased from 15.9 to 10.5, RDI decreased from 23.2 to 14.9, and the mean, lowest O2 saturation increased from 85, 93 to 92, 97 (p<0.05). The RDI was reduced to 10 or less in 40% of patients. Conclusion:LAUP is an efective method for the management of mild OSAS. Authors have demonstrated long-term improvement in subjective and polysomnographic measures. (Korean J Otolaryngol 2002;45:144-8)