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Backgrounds and Objectives:The change of voice quality on menstrual cycle is regarded as general in professionals. The primary objective of this study is to evaluate the changes of acoustic parameters during menstrual cycle in general population. Methods:Twenty young adults were asked to produce vowel /a/, /i/ , and /u/ and to read book audibly at the proliferative yzed by the Computerized Speech Lab. (CSL, Kay Elemetrics, Model 4300B, USA). The statistical analyses were performed using paired t-test to compare several variables of data. Results:Compared with the acoustic parameters between two periods, there were no significant differences in all subjects. But the acoustic parameters with book-reading loudly during menstrual cycles revealed slight changes in voice quality. Conclusion:The change of voice quality, especialy the fatigue of voice may be concerned with menstrual cycle, so more careful voice habituation was required during the menstrual period. (Korean J Otolaryngol 2002;45:285-8)