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Vascular neoplasms are the most comon non-epithelial tumors in the nasal and paranasal regions. However, heman-giope-ricytomas usually occur in the retroperitoneum or in the thigh and are uncommon in the nasal cavity and paranasal sinuses. Nasal hemangiopericytoma-like (HPCL) tumors should be differentiated from typical hemangiopericytomas. HPCL tumors, a distinctive variety of vascular neoplasm, often originate in a paranasal sinus and extend into the nasal cavity secondarily. mptoms of nasal obstruction and epistaxis. Microscopically, HPCL tumors are composed predominantly of spindle cells and lack nuclear or cytoplasmic pleomorphism, mitotic activity, hemorhage, or necrosis demonstrating a vascular architecture. We report a rare case of HPCL tumor originating from nasal septum in a 45-year-old man with the following immunohisto-chemical features:vimentin (+) , CD34 (+) , S-100 protein (-) , desmin (-) , factor VIII-related antigen (-) , and fuchino-(Korean J Otolaryngol 2002;45:821-4)