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To investigate effects of A. gmelinion the 14-day CCl4 induced hepatotoxicity, extracts were prepared in 3ml saline at the dose of 5,000 mg/kg b.w. to administer orally once daily. Each concentration(5:5, 2.5:7.5, 1:9, CCl4 : olive oil v/v) of CCl4 was orally administered with 2.5 ml/kg b.w., During the experiment, halves ofthe rats were sacrificed every 7 day and hemanalysis was done. On the 7th day, hemanalysis showed followingrecovery values; AST 52.6~ 61.4%, ALT 55.9~ 86.1%, ALP 46.0~ 70.9%, BUN 75.7~ 100.0%, TBIL55.2~ 96.1%, TCHO 38.0~ 63.7%, and TG 55.2~ were GOT 37.7~ 43.1%, GPT 19.8~ 45.9%, ALP 58.1~ 95.9%, BUN 57.6~ 100.0%, TBIL 78.6~100.0%, TCHO 56.9~ 100.0%, and TG 10.0~ 51.2%. By histological examination of liver, hydropicdegeneration, fatty change, lipid accumulation and necrosis were also recovered by administration of A.gmeliniextract.