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The purpose of this study was to investigate the influence of morphological characteristic and motor abilities of college male students(n=38) to predict initial acceleration rate and maximal velocity in 50m sprint. For the tests of motor abilities several measures of lower extremities were administered in addition to anthropometric measurement. The data was analyzed using multiple linear regression analysis on SPSS statistical package. Although the somatotype of the subjects was classified as mesomorphic-endomorphy, body mass index(BMI) was classified as desirable BMI and %fat was under average classification. The correlation coefficient of initial acceleration rate with independent variable was very low except sargent jump(-0.533), side step, and endomorphy. The correlation coefficient of maximal velocity with independent variables showed that push up was best related with maximal velocity. As a result of multiple linear regression analysis sargent jump, endormorphy, and waist girth were selected as predictive variables to initial acceleration rate. On the other hand push up and endormorphy were entered as predictive variables for maximal velocity. In conclusion there exist different predictive factors to initial acceleration rate and maximal velocity, and anthropometric factors are not appropriate predictor for sprint performance. Also, the training status is another important consideration for this kind of research.