ABSTRACT

The aim of this study was to assess the antioxidant activity and whitening efficacy of ethanolic extract of herbcomplex (Oenothera laciniata, Phellinus linteus and Glycyrrhiza uralensis Fischer). The antioxidant activity wasevaluated by DPPH-radical inhibition activity, xanthine oxidase (XO) inhibition activity, superoxide dismutase (SOD)-like activity, and ABTS radical inhibition activity. Whitening efficacy was evaluated by mushroom tyrosinase inhibitionactivity. In the antioxidant activities of ethanolic extract of herb complex at 1,000 μg/mL concentration, DPPH radicalinhibition activity was over 80% and similar to that of BHA, positive control. XO inhibition activity was over 90%. TheSOD-like activity was over 30%. ABTS radical inhibition activity was over 95%. The ethanolic extract of herb complexreduced the mushroom tyrosinase activity in a dose-dependant manner, showing a inhibitory rate over 60% at 1,000μg/mL concentration compared to the untreated control. The ethanolic extract of herb complex did not affect on cellgrowth at test concentrations (0~1,000 μg/mL). From these results, it was found that the ethanolic extract of herbcomplex had a good antioxidant activity and whitening efficacy. Hence, it could be used as cosmetic ingredients for skinwhitening and/or skin anti-ageing.

KEYWORD

Antioxidant activity, Glycyrrhiza uralensis Fischer, Oenothera laciniata, Phellinus linteus, Whitening efficacy

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