초록

This study investigated the effects of supplementation of the nutraceutical product Eurycoma longifolia Jack on recreational athletes’ endurance running capacity and physiological responses in the heat. Twelve Malaysian healthy male recreational athletes (Age: 23.3 (3.7) years old; VO2max: 45.1 (8.1) ml.kg-1.min-1) were recruited in this double blind, placebo-controlled, cross-over study. Subjects completed two endurance running trials in the heat (31°C, 70% relative humidity), performed on separate days, after consuming either 2 capsules of Eurycoma longifolia Jack (75 mg per capsule) or a placebo per day for 7 days before and one hour prior to the experimental trial. On trial day, after 5 minutes of warm-up at 50 % VO2max, the subjects were requested to run on the treadmill at 60 % VO2max for 60 minutes. This was immediately followed by a 20-minute time trial for determining endurance running capacity. Blood samples were taken before warm up, after warm-up, and every 20 minutes during the trial. Statistical analysis was performed using one-way ANOVA with repeated measures. Results showed that the endurance running capacity of E. longifolia was not significantly different from that of the placebo trial. Similarly, oxygen uptake, heart rate, skin temperature, tympanic temperature, ratings of perceived exertion, haemoglobin concentration, haematocrit level, plasma glucose concentration, and plasma free fatty acid concentration were not significantly different between the trials. These findings suggested that supplementation of the E. longifolia product at a dosage of 150 mg.day-1 for 7 dayshas not provided beneficial effects on endurance running capacity and physiological responses of recreational athletes in the heat. Higher dosage and longer duration of supplementation of the product may be warranted to evaluate further its endurance capacity during exercise.

키워드

Ergogenic aids, Eurycoma longifolia Jack, endurance running capacity

참고문헌(76)open

  1. [학술지] Ahrendt,M.D / 2001 / Ergogenic Aids: Counseling the Athlete / Am. Fam. Physician 63 (5) : 913 ~ 922

  2. [학술지] Allen, J. D. / 1998 / Ginseng supplementation does not enhance healthy young adults' peak aerobic exercise performance / J. Am. Coll. Nut. 17 : 462 ~ 466

  3. [학술지] Ang, H. H. / 1999 / Studies on the anxiolytic activity of Eurycoma longifolia Jack roots in mice / Jpn. J. Pharmacol. 79 (4) : 497 ~ 500

  4. [학술지] Ang, H. H. / 2001 / Effects of Eurycoma longifolia Jack on laevator ani muscle in both uncastrated and testosterone-stimulated castrated intact male rats / Arch. Pharm. Res. 24 (5) : 437 ~ 440

  5. [학술지] Ang, H. H. / 2002 / Effect of Eurycoma longifolia Jack on libido in middle-aged male rats / J. Basic Clin. Physiol. Pharmacol. 13 (3) : 249 ~ 254

  6. [학술지] Ang, H. H. / 2002 / Effect of Eurycoma longifolia Jack on orientation activities in middle-aged male rats / Fundam. Clin. Pharmacol. 16 (6) : 479 ~ 483

  7. [학술지] Ang, H. H. / 2001 / Aphrodisiac evaluation in non-copulator male rats after chronic administration of Eurycoma longifolia Jack / Fundam. Clin. Pharmacol. 15 (4) : 265 ~ 268

  8. [학술지] Ang, H. H. / 1997 / Eurycoma longifolia Jack enhances libido in sexually experienced male rats / Exp. Anim. 46 (4) : 287 ~ 290

  9. [학술지] Ang, H. H. / 1998 / Eurycoma longifolia increases sexual motivation in sexually naive male rats / Arch. Pharm. Res. 21 (6) : 779 ~ 781

  10. [학술지] Ang, H. H. / 1998 / Eurycoma longifolia Jack and orientation activities in sexually experienced male rats / Biol. Pharm. Bull. 21 (2) : 153 ~ 155

  11. [학술지] Ang, H. H. / 1995 / In vitro anti-malarial activity of quassinoids from Eurycoma longifolia against Malaysian chloroquine-resistant Plasmodium falciparum isolates / Planta Med. 61 (2) : 177 ~ 178

  12. [학술지] Ang, H. H. / 2000 / Effects of Eurycoma longifolia Jack (Tongkat Ali) on the initiation of sexual performance of inexperienced castrated male rats / Exp. Anim. 49 (1) : 35 ~ 38

  13. [학술지] Ang, H. H. / 2002 / Quassinoids from Eurycoma longifolia / Phytochemistry 59 (8) : 833 ~ 837

  14. [학술지] Ang, H. H. / 2001 / Evaluation of the potency activity of aphrodisiac in Eurycoma longifolia Jack / Phytother. Res. 15 (5) : 435 ~ 436

  15. [학술지] Ang, H. H. / 2003 / Eurycoma longifolia Jack enhances sexual motivation in middle-aged male mice / J. Basic Clin. Physiol. Pharmacol. 14 (3) : 301 ~ 308

  16. [학술지] Ang, H. H. / 2004 / Sexual arousal in sexually sluggish old male rats after oral administration of Eurycoma longifolia Jack / J. Basic Clin. Physiol. Pharmacol. 15 (3) : 303 ~ 309

  17. [학술지] Ang, H. H. / 2003 / Effects of Eurycoma longifolia Jack on sexual qualities in middle aged male rats / Phytomedicine 10 (6) : 590 ~ 593

  18. [학술지] Angus, D. J. / 2001 / Effect of carbohydrate ingestion on glucose kinetics during exercise in the heat / J. Appl. Physiol. 90 (2) : 601 ~ 605

  19. [학술지] Bedir, E. / 2003 / Eurycomanoside: A new quassinoid-type glycoside from the roots of Eurycoma longifolia / Chem. Pharm. Bull. (Tokyo) 51 (11) : 1301 ~ 1303

  20. [학술지] Bell, D. G. / 2003 / Effect of repeated caffeine ingestion on repeated exhaustive exercise endurance / Med. Sci. Sports Exerc. 35 (8) : 1348 ~ 1354

  21. [학술지] Bell, D. G. / 1998 / Effects of caffeine, ephedrine and their combination on time to exhaustion during high-intensity exercise / Eur. J. Appl. Physiol. Occup. Physiol. 77 (5) : 427 ~ 433

  22. [학술지] Bell, D. G. / 2000 / Reducing the dose of combined caffeine and ephedrine preserves the ergogenic effect / Aviat. Space Environ. Med. 71 (4) : 415 ~ 419

  23. [학술지] Below, P. R. / 1995 / Fluid and carbohydrate ingestion independently improve performance during 1 hour of intense exercise / Med. Sci. Sports Exerc. 27 : 200 ~ 210

  24. [학술지] Bucci, L. R / 2000 / Selected herbals and human exercise performance / Am. J. Clin. Nutr. 72 : 624S ~ 636S

  25. [단행본] Bursztyn,P.G / 1990 / Metabolism In: Physiology or sports people-a serious users’ guide to the body / Manchester University Press : 54 ~ 59

  26. [학술지] Carter, J. / 2003 / Carbohydrate supplementation improves moderate and high-intensity exercise in the heat / Pflugers. Arch 446 : 211 ~ 219

  27. [학술지] Chan, K. L. / 1989 / A Quassinoid Glycoside from the Roots of Eurycoma longifolia / Phytochemistry 28 : 2857 ~ 2859

  28. [학술지] Chan, K. L. / 1986 / Plants as sources of antimalarial drugs. Part 31 Eurycoma longifolia / Planta Med. 52 (2) : 105 ~ 107

  29. [학술지] Chen, C. K. / 2004 / High ambient temperature impairs endurance performance in heat-adapted recreational athletes / Asian J of Exerc and Sports Sci. 1 (1) : 53 ~ 61

  30. [학술지] Chen, C. K. / 2006 / Effects of palm vitamin E supplementation on exercise-induced oxidative stress and endurance performance in the heat / J. Sports Sci. Med. 5 : 629 ~ 639

  31. [학술지] Choudhary, M. I. / 1997 / Elixirs of love / Chem. Br. 33 (10) : 25 ~ 27

  32. [학술지] Cohen, B. S. / 1996 / Effects of caffeine ingestion on endurance racing in heat and humidity / Eur. J. Appl. Physiol. Occup. Physiol. 73 (3) : 358 ~ 363

  33. [인터넷자료] Coleman,E / Fueling during exercise / com

  34. [학술지] Coyle, E.F. / 1986 / Muscle glycogen utilisation during prolonged strenuous exercise when fed carbohydrate / J. Appl. Physiol. 61 : 165 ~ 172

  35. [학술지] David, O. K. / 2003 / Ginseng: Potential for the enhancement of cognitive performance and mood / Pharmacol. Biochem. Behav. 75 : 687 ~ 700

  36. [학술지] Engels, H. J. / 1997 / No ergogenic effects of ginseng (Panax ginseng C.A. Meyer) during graded maximal aerobic exercise / J. Am. Diet. Assoc. 97 : 1110 ~ 1115

  37. [학술지] Engels, H. J. / 2001 / Effects of ginseng supplementation on supramaximal exercise performance and short-term recovery / J. Strength Cond. Res. 15 (3) : 290 ~ 295

  38. [학술지] Falk, B. / 1989 / The effect of caffeine ingestion on physical performance after prolonged exercise / Eur. J. Appl. Physiol. Occup. Physiol. 59 (3) : 168 ~ 173

  39. [학술지] Farouk, A. E. / 2007 / Antibacterial activity of Eurycoma longifolia Jack. A Malaysian medicinal plant / Saudi Med. J. 28 (9) : 1422 ~ 1424

  40. [학술지] Febbraio, M. A. / 1996 / Effect of CHO ingestion on exercise metabolism and performance in different ambient temperatures / Med. Sci. Sports Exerc. 28 (11) : 1380 ~ 1387

  41. [학술지] Flinn, S. / 1990 / Caffeine ingestion prior to incremental cycling to exhaustion in recreational cyclists / Int. J. Sports Med. 11 (3) : 188 ~ 193

  42. [학술지] Galloway, S. D. / 1997 / Effects of ambient temperature on the capacity to perform prolonged cycle exercise in man / Med. Sci. Sports Exerc. 29 (9) : 1240 ~ 1249

  43. [학술지] Hamzah, S. / 2003 / The ergogenic effects of Eurycoma longifolia Jack: A pilot study / Br. J. Sports Med. 37 (5) : 465 ~ 465

  44. [학술지] Hargreaves, M. / 1996 / Effect of fluid ingestion on muscle metabolism during prolonged exercise / J. Appl. Physiol. 80 (1) : 363 ~ 366

  45. [학술지] Husen, R. / 2004 / Screening for antihyperglycaemic activity in several local herbs of Malaysia / J. Ethnopharmacol. 95 (2) : 205 ~ 208

  46. [단행본] Jagananth, J. B. / 2000 / Herbs: The Green Pharmacy of Malaysia. In Vinpress Sdn. Bhd. and Malaysian Agriculture Research and Development Institute (MARDI) / Kuala Lumpur : 45 ~ 46

  47. [학술지] Jentjens, R. L. P. G. / 2002 / Heat stress increases muscle glycogen use but reduces the oxidation of ingested carbohydrates during exercise / J. Appl. Physiol. 92 (4) : 1562 ~ 1572

  48. [학술지] Kardono, L. B. S. / 1991 / Cytotoxic and antimalarial constituents of the roots of Eurycoma longifolia / J. Nat. Prod. 54 : 1360 ~ 1367

  49. [학술지] Keith, R. E. / 1982 / Lung function and treadmill performance of smoking and nonsmoking males receiving ascorbic acid supplements / Am. J. Clin. Nutr. 36 : 840 ~ 845

  50. [학술지] Kuo, P. C. / 2003 / Cytotoxic and antimalarial beta-carboline alkaloids from the roots of Eurycoma longifolia / J. Nat. Prod. 66 (10) : 1324 ~ 1327

  51. [학술지] Lawrence, J. D. / 1975 / Effects of alpha-tocopherol acetate on the swimming endurance of trained swimmers / Am. J. Clin. Nutr. 28 : 205 ~ 208

  52. [단행본] McArdle, W. D. / 2007 / Individual difference and measurement of exercise capacities. In: Exercise Physiology: Energy, Nutrition, and Human Performance / Lippincott Williams & Wilkins : 229 ~ 239

  53. [학술지] Montain, S. J. / 1992 / Influence of graded dehydration on hyperthermia and cardiovascular drift during exercise / J. Appl. Physiol 73 : 1340 ~ 1350

  54. [학술지] Morris, A. C. / 1996 / No ergogenic effect of ginseng ingestion / Int. J. Sport. Nutr 6 : 263 ~ 271

  55. [학술지] Nadel, E. R. / 1980 / Effect of hydration state of circulatory and thermal regulations / J. Appl. Physiol 49 : 715 ~ 721

  56. [학술지] Nielsen, B. / 1997 / Acute and adaptive responses in humans to exercise in a warm, humid, environment / Pflugers Arch 434 : 49 ~ 56

  57. [학술지] Ooi, F. K. / 2001 / Effects of a herbal ergogenic drink on cycling performance in young cyclists / Mal.J. Nutr. 7 (1) : 33 ~ 40

  58. [학술지] Ooi, F. K. / 2003 / Effects of a herbal drink on cycling endurance performance / Mal. J. Nutr. 10 (1) : 78 ~ 85

  59. [학술지] Oostenbrug, G. S. / 1997 / Exercise performance, red blood cell deformability, and lipid peroxidation: Effects of fish oil and vitamin E / J. Appl. Physiol. 83 : 746 ~ 752

  60. [학술지] Osman, A. / 2003 / Genetic diversity of Eurycoma longifolia inferred from single nucleotide polymorphisms / Plant Physiol. 131 (3) : 1294 ~ 1301

  61. [학술지] Parcell, A. C. / 2004 / Cordyceps Sinensis (CordyMAx Cs-4) supplementation does not improve endurance exercise performance / Int. J. Sport Nutr. Exerc. Metab. 14 : 236 ~ 242

  62. [학술지] Peake, J. / 2008 / Carbohydrate gel ingestion and immunoendocrine responses to cycling in temperate and hot conditions / Int. J. Sport Nutr. Exerc. Metab. 18 (3) : 229 ~ 46

  63. [학술지] Powers, H. J. / 1987 / Bicycling performance in Gambian children: Effects of supplements of riboflavin or ascorbic acid / Hum. Nutr. Clin. Nutr. 41 (1) : 59 ~ 69

  64. [학술지] Ramanathan,N.L / 1964 / A New Weighting System for Mean Surface Temperature of the Human Body / J. Appl. Physiol. 19 : 531 ~ 533

  65. [학술지] Saat, M. / 2005 / Effects of exercise in the heat on thermoregulation of Japanese and Malaysian males / J. Physiol. Anthropol. Appl. Human Sci. 24 (4) : 267 ~ 275

  66. [학술지] Sasaki, H. / 1987 / Effects of sucrose or caffeine ingestion on running performance and biochemical responses to endurance running / Int. J. Sports Med. 8 (3) : 203 ~ 207

  67. [학술지] Sawka, M. N. / 1999 / Influence of body water and blood volume on thermoregulation and exercise performance in the heat / Exerc. Sport Sci. Rev 27 : 167 ~ 218

  68. [학술지] Sawka, M. N. / 2007 / American College of Sports Medicine position stand: Exercise and fluid replacement / Med. Sci. Sports Exerc 39 : 377 ~ 390

  69. [학술지] Shapiro, Y. / 1990 / Field and clinical observations of exertional heat stroke patients / Med. Sci. Sports Exerc. 22 (1) : 6 ~ 14

  70. [학술지] Tee, T. T. / 2007 / F16, a fraction from Eurycoma longifolia Jack extract, induces apoptosis via a caspase-9-independent manner in MCF-7 cells / Anticancer Res. 27 (5A) : 3425 ~ 3430

  71. [학술지] Titlow, L. W. / 1991 / Failure of caffeine to affect metabolism during 60 min submaximal exercise / Sports Sci. 9 (1) : 15 ~ 22

  72. [학술지] Tokmakidis, S. P. / 2008 / Effects of carbohydrate ingestion 15 min before exercise on endurance running capacity / Appl. Physiol. Nutr. Metab 33 : 441 ~ 449

  73. [학술지] Webster,M.J / 1998 / Physiological and performance responses to supplementation with thiamin and pantothenic acid derivatives / Eur. J. Appl. Physiol. Occup. Physiol. 77 (6) : 486 ~ 491

  74. [학술지] Wee, S. L. / 1999 / Influence of high and low glycemic index meals on endurance running capacity / Med. Sci. Sports Exerc 31 : 393 ~ 399

  75. [단행본] Wilmore, J. H. / 2008 / Obesity, Diabetes, and Physical Activity. In: Physiology of Sport and Exercise / Human Kinetics : 492 ~ 516

  76. [학술지] Yaspelkis, B. B. III / 1991 / Effect of carbohydrate supplements and water on exercise metabolism in the heat / J. Appl. Physiol. 71 (2) : 680 ~ 687